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Pipeline AIM Biologicals AEZS-150 AEZS-130 (Macimorelin) Macimorelin Dx
AEZS-150 (Delayed Clearance Parathyroid Hormone Fusion Polypeptides DC-PTH)
Treatment of Chronic Hypoparathyroidism
AEZS-150 (DC-PTH) is the active part of the parathyroid hormone, PTH1-34, linked to a modified version of the growth hormone binding protein (GHBP) with the goal of replacing the PTH activity for one week.
We envision self-administered weekly injections of AEZS-150 to maintain normal serum calcium, phosphate levels, and urinary calcium secretion in patients with hypoparathyroidism.
Hypoparathyroidism
Affects ~23-37 in every
100,000 people in
the US and Europe
Results in Renal dysfunction; Muscle cramping; Twitching; Seizures; Cardiac arrhythmias
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